People who use a vertical gaming mouse on a causal basis may not know how important they are. However, anyone who uses vertical mice consistently will be able to tell you why they’re so important. They feature a design that allows you to relax your wrist and forearm, and this can lead to a higher comfort level over a period of heavy use. If you’ve never had a vertical gaming mouse, this is for you. We’ll review the top 10 vertical gaming mice available including pros, cons, and specifications. Our short buyer’s guide will tell you all you need to know about buying the best vertical gaming mouse for yourself.
Best Vertical Gaming Mouse Buyer’s Guide
Why Use a Vertical Gaming Mouse?
Repetitive motions with your wrists or hands can lead to painful medical problems over the course of a few years. Things like carpal tunnel syndrome and repetitive stress injuries are common. If they progress far enough, they may even require surgery to fix. This is why a vertical mouse is so important. It wasn’t so much of a problem in the golden days of the ‘atari stick’ or the ‘kempston joystick’, and maybe that is why the modern vertical wireless mouse (even the wired ones) resemble, to some degree the joysticks of yesteryear.
Vertical Gaming Mice Specifications
Buttons
Gaming mice usually have between four and eight programmable buttons that you can set up to perform simple tasks with a click. You do want to pay attention to where the buttons are positioned on the mouse. This will give you a good idea of how easy it will be to operate them when you need to.
Compatibility
Not all vertical gaming mice work with all operating systems. You want to pick one that you know is going to work with whichever operating system you have. A lot of these mice work with Windows, MAC OS, and Linux. At the very least, it should work with Windows and MAC OS.
DPI
DPI stands for dots per inch. This measures how fast and how accurate your mouse is when you move it. The higher you set the DPI, the more sensitive your mouse will be to movement. This is important for people who do precision work or gamers. The best vertical mouse should have adjustable DPI settings.
Wired or Wireless
Do you want your mouse to run wireless or on a cord? A cord can be more restrictive in terms of movement. But, you’ll have greater connectivity because it’ll plug right into your machine. You can also get a more reliable connection with wired. A wireless mouse allows for greater movement, but it can connect less and less the farther away you get. If you opt for wireless, another consideration is if the mouse comes with a rechargeable battery built-in or if it will require AA or AAA batteries.
Best Vertical Gaming Mouse – Comparison Table
 | Anker Ergonomic Optical USB Wired Vertical Mouse | Features next and previous buttons Has DPI Resolution Optical Tracking Technology Comes with lifetime tech support | 4.5 out of 5 |
 | J-Tech Digital V628Scroll Endurance Mouse Ergonomic Vertical USB Mouse | Compatible with a wide variety of systems Palm guard is removable Has a heavier and more solid feel | 4.3 out of 5 |
 | J-Tech Digital Vertical Ergonomic Mouse | Adjustable DPI Puts hand in a neutral position Wide operating system compatibility | 4.3 out of 5 |
 | Logitech MX Vertical Wireless Mouse | Puts hand at a comfortable 57-degree angle Textured grip Wide compatibility | 4.6 out of 5 |
 | Evoluent VM4R Vertical Mouse | Comfortable hand position Ergonomic sculpt Programmable buttons | 4.4 out of 5 |
 | OMOTON Ergonomic Mouse | Anti-slip pad High DPI works on most surfaces Quick-change sensitivity button | 4.5 out of 5 |
 | seenda Wireless Vertical Ergonomic Mouse | Ergonomic Design Mouse 1 Mouse for Multi-purpose Noiseless Click & Voiced Click | 4.5 out of 5 |
 | ZLOT Vertical Gaming Mouse | Ergonomic Vertical Design Programmable and customizable 11 programmable buttons and On-board memory. | 4.3 out of 5 |
 | TRELC Gaming Mouse | Ergonomic Vertical Mouse 5 Direction Rocker Programmable Buttons | 4.3 out of 5 |
 | eirix Ergonomic Vertical Mouse | Ergonomically Designed Vertical Mouse USB Wireless Mouse and Removable Palm Rest Adjustable DPI Level | .4 out of 5 |
 | Delux Ergonomic Design Wired Vertical Optical Gaming Mouse | Comes with six easy to reach buttons Palm rest is removable RGB Lighting | 4.3 out of 5 |
 | Anker 2.4G Wireless Vertical Ergonomic Optical Mouse, 800 / 1200 /1600 DPI | Easy to use - plug and play Good wireless range Good battery life | 4.3 out of 5 |
 | Jelly Comb Wireless Vertical Mouse 2.4G High Precision | Really simple and inviting design Highly responsive Widely compatible | 4.5 out of 5 |
10 Best Vertical Gaming Mouse Reviews
Anker Ergonomic Optical USB Wired Vertical Mouse
This highly sensitive vertical gaming mouse has 1,000/1,600 DPI Resolution Optical Tracking Technology built in. It gives you next and previous buttons as you get the convenience of a webpage scrolling experience in a mouse. You get a 4.9 foot USB cable attachment as well as an 18-month guarantee. Additionally, you’ll also enjoy free lifetime tech support when you purchase this mouse.
Specifications
- Compatibility – Windows 8, 7, Vista, XP, 2000, Linux, Mac OS X
- Cord Length – 4.9 Foot USB – (requires USB Port)
- Pointer Speed – 1,000/1,600
- Weight – 5.3 Ounces
Pros
- Features next and previous buttons
- Has DPI Resolution Optical Tracking Technology
- Comes with lifetime tech support
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J-Tech Digital V628Scroll Endurance Mouse Ergonomic Vertical USB Mouse
This vertical mouse comes with three different DIP adjustments. It is designed to be a plug and play model without having to worry about any additional installation process. You’ll get an anti-sweat and anti-skid base design that is removable as well. This vertical mouse comes in three different style choices, and the lighting makes it easy to see.
Specifications
- Compatibility – Windows 8, 7, Vista, XP, 2000, Linux, Mac
- Cord Length – USB Plugin (requires USB Port)
- Pointer Speed – 600/1,000/1,600
- Weight – 10.9 Ounces
Pros
- Compatible with a wide variety of systems
- Palm guard is removable
- Has a heavier and more solid feel
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J-Tech Digital Vertical Ergonomic Mouse
This vertical mouse from J-Tech is beautifully designed. Every detail is thought-out to provide optimal comfort while making your desk look like a tech-lovers dream.
The unique ergonomic shape of the mouse is engineered to fit the contours of your hand. It put your hand and forearm in a “handshake” position. This position is neutral and doesn’t cause fatigue on your arm or wrist.
There are several buttons to take advantage of. On one side, you’re getting a traditional left and right mouse click with a scroll wheel. But on the other side, you’re also getting two thumb buttons. Great for gaming and work, you can easily program the buttons to fit your needs. With five memory slots, multiple people can use the mouse without having to worry about reprogramming everything with each use. Plus, there are several DPI settings for sensitivity control!
The most standout feature of this mouse is the lighting system. Custom RGB lights outline the mouse, providing a pop of customizable color.
Pros:
- Adjustable DPI
- Puts hand in a neutral position
- Wide operating system compatibility
- Removable palm rest
- Non-slip bottom
Cons:
- May not be suitable for smaller hands
- The sensor can be spotty on some surfaces
Specifications:
- Wired
- Four buttons and scroll wheel
- Custom RGB lighting
- Five memory profile slots
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Logitech MX Vertical Wireless Mouse
Here’s a sleek mouse that offers a professional touch to your desk setup. Like other vertical mice, the main draw of this unit is the hand positioning. It angles your hand at approximately 57 degrees. This is a neutral position that may help reduce fatigue and strain.
Texturized grip on the side of the mouse offers greater comfort as you use the mouse. Meanwhile, the positioning of the buttons provides a natural user experience. The right side features a traditional mouse layout complete with two buttons and a scroll wheel. On the back, you have two programmable buttons that you can use for shortcuts, game inputs, and more.
One cool feature is the quick cursor speed switch on top. The mouse has a fixed DPI of 4,000, which is great for getting accurate inputs. But, the cursor speed adjustments provide even more versatility. You can make adjustments on the fly without having to dig into Logitech’s proprietary software.
Pros:
- Puts hand at a comfortable 57-degree angle
- Textured grip
- Wide compatibility
- Programmable
- Charges fast
Cons:
- Buttons and wheel can be hard to press
- Fixed DPI
Specifications:
- Wired USB connection
- Connects to Bluetooth or USB receiver
- USB-C charging
- Integrated cursor speed switch
- 4000 DPI sensor
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Evoluent VM4R Vertical Mouse
Evoluent is no stranger to creating some high-quality vertical mice. The VM4R model is no different. This accessory takes on a unique molded shape. While it looks unconventional, it offers exceptional comfort. It’s molded to fit into a loose hand.
All of the buttons are positions within reach. Speaking of which, this mouse comes with six programmable buttons. There are also a couple of function buttons that can increase functionality tenfold! Take, for example, the pointer speed button on the front. With a press of a button, you can cycle through different sensitivity speeds.
On the opposite side of the mouse, an LED indicator light lets you know what setting your on. Cycle through the options based on the task at hand for ultimate control!
Pros:
- Comfortable hand position
- Ergonomic sculpt
- Programmable buttons
- LED speed indicator
Cons:
- The finish is prone to damage
- Light may be too bright for some
Specifications:
- Wired USB connection
- Six buttons
- Hyperspeed scrolling
- Integrated LEDs and cursor speed switch
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OMOTON Ergonomic Mouse
From Omoton is this affordable vertical mouse. It doesn’t have all the bells and whistles as some other options out there. But, it covers your bases and comes with an impressively low price tag!
Despite its affordability, this mouse has several versatility features. The first is multiple DPI settings. You can choose from 800, 1,600, and 2,400. Best of all, you’re able to switch between the sensitivity settings on the fly. A dedicated button on the right-hand side allows you to make changes to suit your needs without having to fiddle with driver settings.
You also have a couple of choices for connectivity. This mouse has Bluetooth connectivity built right in. You can also use the included USB dongle, which is low-profile and slips into the bottom of the device. The mouse uses simple replaceable batteries. However, there is a power switch on the bottom and a power-saving mode to help you make the most out of your batteries!
Pros:
- Anti-slip pad
- High DPI works on most surfaces
- Quick-change sensitivity button
- Four buttons and scroll wheel
- Compact design
- Power-saving mode
Cons:
- Not programmable
- Not rechargeable
Specifications:
- Wireless
- Replaceable batteries
- USB and Bluetooth connectivity
- Multiple DPI settings up to 2,400
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seenda Wireless Vertical Ergonomic Mouse
Whether working or playing, this ergonomic mouse can keep up with your demands. The vertical shape alleviates pain in your shoulder and wrist because it puts your hand in the right position. Thanks to Bluetooth 5.0 technology, you can connect up to five devices to the mouse in seconds and use them whenever you want. The mouse has a built-in switch that lets you switch back and forth between those devices. Each of the nine buttons has a design that cuts back on clicks to reduce the noises that it makes. It also has a rechargeable battery that helps you charge the battery as you use the mouse or while you sleep.
Pros:
- Ergonomic Design Mouse
- 1 Mouse for Multi-purpose
- Noiseless Click & Voiced Click
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Other guides you should check out
Best Wireless Charging Mouse Pad
Best Wireless Keyboard and Mouse Combos
ZLOT Vertical Gaming Mouse
You can move effortlessly through all of your games with this vertical mouse that has an ergonomic grip to keep you in the right position as you play. It keeps your wrist and forearm stable and stops you from twisting, which is a motion that can cause some pain. The mouse has an IR sensor that detects the slightest of movements and a DPI level that you can adjust in five ways. Thanks to the on-board memory, it remembers the settings that you used when you turn it off. This mouse also has options that let you program it to meet your needs as well as a belt that changes colors as you move it.
Pros:
- Ergonomic Vertical Design
- Programmable and customizable
- 11 programmable buttons and On-board memory.
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TRELC Gaming Mouse
With this gaming mouse, you get both the speed and precision that you want when playing any type of game. The wired design offers the plug-and-play use that you want, which lets you plug it into an open port and start playing immediately. It mimics the natural grip that your hand has and puts both your hand and wrist in a natural position to reduce discomfort. Each of the five rockers will help you do different things and take the place of your keyboard. With the thumb control, you can move quickly and change where your character goes. This mouse is compatible with all types of games and has built-in light modes. It has sensors that adjust the velocity, too.
Pros:
- Ergonomic Vertical Mouse
- 5 Direction Rocker
- Programmable Buttons
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eirix Ergonomic Vertical Mouse
Get as far into your games as you want with this ergonomic mouse. The vertical design offers a different experience than you had before and puts your hand in the right position to reduce discomfort. This allows you to move your wrist and hand in natural ways and see the characters on your screen quickly respond. A built-in palm rest adds to your overall comfort and is removable for those who dislike it. You can adjust the polling rate from 800 to 3200 to make it work with your games. This mouse also has an LED light for use at night and comes with a Nano receiver for syncing it to your computer. You also get a USB cable for convenient charging of the mouse’s battery.
Pros:
- Ergonomically Designed Vertical Mouse
- USB Wireless Mouse and Removable Palm Rest
- Adjustable DPI Level
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Delux Ergonomic Design Wired Vertical Optical Gaming Mouse
This vertical mouse is designed to fit to your hand comfortably. There are six easy to reach buttons. You don’t have to contort your arm to reach them. You can choose from five different sensitivity levels that give you a smooth and seamless experience. The mouse and the palm rest feature no-slip grip with ridges. Additionally, the palm and wrist rest is removable.
Specifications
- Compatibility – Windows, Limited For Mac OS (side button’s don’t work on Mac)
- Connectivity – Wired USB
- Pointer Speed – 800/1,200/1,600/2,400/4,000 DPI
- Weight – 7.4 Ounces
Pros
- Comes with six easy to reach buttons
- Palm rest is removable
- RGB Lighting
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Anker 2.4G Wireless Vertical Ergonomic Optical Mouse, 800 / 1200 /1600 DPI
The Anker 2.4G Wireless Vertical Mouse is similar to it’s wired brother at the start of the post but with a few notable differences. First, the obvious difference that this one is wireless. It also has slightly different DPI levels at 800/1200 and 1600. This vertical mouse connects via a USB dongle to your computer, and requires 2 AAA batteries. To help with power saving, the mouse will shut down after 8 minutes of inactivity, and can be awoken by pressing the left or right button. It’s ergonomically sound, a fan favourite, simple and easy to use from the get go.
Specifications
- Compatibility – Windows, Linux, Mac OS
- Cord Length – Wireless USB
- Pointer Speed – 800/1,200/1,600
- Weight – 3.36 Ounces
Pros
- Easy to use – plug and play
- Good wireless range
- Good battery life
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Jelly Comb Wireless Vertical Mouse 2.4G High Precision
The Jelly Comb Wireless Vertical Mouse is another firm fan favourite. It’s simple design may seem unassuming, but in the simplicity lies the reassurance of familiarity. It look and, to a degree, feels like a normal mouse and that familiar simple design takes any intimidation out of ‘giving it a go’. The ergonomic feel and shape of the vertical mouse, aligns it firmly in your palm, with great support for your wrist and thumb as you grip.
The mouse requires a single AA battery to operate, and there is a slot in the battery compartment to store the USB dongle when not in use. The Jelly Comb mouse is widely compatible, highly responsive and very stable. No wonder it’s a fan favorite.
Specifications
- Compatibility – Windows, Linux, Mac OS
- Cord Length – Wireless USB (1 AA battery required)
- Pointer Speed – 800/1,200/1,600
- Weight – 3.2 Ounces
Pros
- Really simple and inviting design
- Highly responsive
- Widely compatible
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